detection, diagnosis and treatment of diseases
Detection and Diagnosis
Lab on chips help detection and diagnosis of diseases more efficiently
Nanowire and cantilever lab on chips help in early detection ofcancer biomarkers
Receptor-mediated endocytosis of the nanocarrier(1)
Exocytosis of the nanocarrier(1a)
Dissociation, acidification, release of the drug into the brain; (1b)
cancer treatments
2. Drugs Detecting Receptors on Cancer Cell’s Surface
The receptors, which is important to cancer targeting, exist not only on the cancer cell’s surface but also on the normal cell’s surface. So we have a potential to mis-treatment.
So, we focused on overcoming of these drawbacks. To overcome these side effects we considered two things.
1. Nano-sized particle
Nano
of heat disease like coronary heart disease, cardiomyopathy, hypertensive heart disease, and so on.
1.2 The principle ofdetecting method using cardiac marker
The principle ofdetecting method is simple. when the heart muscles are damaged by some reasons, the cardiac enzymes existing in heart muscles are emitted in blood vessels. by detecting the change of the concentration of cardiac enzymes
Heart disease
Cardiovascular(heart) disease
- a class of diseases that involve the heart or blood vessels
- the biggest cause of deaths worldwide
(Wikipedia)
Examples :
Coronary heart disease
Cardiomyopathy - diseases of cardiac muscle
Hypertensive heart disease - diseases of the heart secondary to high blood pressure
Heart failure
Cor pulmonale - a failure of the right sid
5.2 Drug Delivery System
5.2.1 Advantage of Nano-drug delivery system
By diagnosis, and for treatment, we need enhanced drug delivery system. Drug delivery system of these days is just eat and let it flow through the body. It is not good at efficiency. Because the digestive system sometimes digest and remove the drug before it reaches to the target.
For enhancing the efficiency of drug
of the potential harm to others arising from interconnectivity and interdependency.
Responsibility: all participants, including policymakers and program designers, are responsible for the security of information systems and networks.
Response: Participants should act in a timely and cooperative manner to prevent, detect and respond to security incidents. Where permissible, this may involve
of only one cantilever surface, as the cantilever resonance frequency change depends on the total mass adsorbed on both sides. In this mode, the microcantilever is used as a microbalance and extremely high sensitivities can be obtained (in the attogram regime), overcoming other similar and well-known mass detectors, such as the quartz crystal microbalance (QCM).[5] In first approximation cantilev
Laparoscopic subtotal gastrectomy and Billroth I
LN meta 없으면 5YSR>97~100%
F/U : 처음 1년간은 3~6개월마다 이후에는 1년에 1~2회 내시경 검사 시행
Op date : 2010. 04. 20
PreOp Dx
Stomach cancer(R/O EGC)
Op name
Laparoscopy Assisted Distal Gastrectomy
Billroth I
95% of all malignant gastric neoplasms
Gastric cancer incidence has decreased worldwide
*’Nano’ means….
Nanometer: one billionth of a meter
Nano-: prefix comes from the Greek word for ‘dwarf’
Chemical, physical, and biological properties that differ from those of their larger, or bulk counterparts
Nanotechnology: The National Nanotechnology Initiative(NNI)-> the science of materials and phenomena in the range of 1 to 100nm in diameter
*Features of ‘nanoparticles